Use Value of Plant Species raised in home gardens in some communities in Southern Kaduna, Kaduna State, Nigeria was determined. A semi-structured questionnaire was used to engage 90 respondents from three communities for data collection on species grow in home gardens in the areas and their traditional or cultural medicine application. Results show that Stomach pain, malaria fever, and typhoid fever diseases were treated with the highest diversity of plant species, including 67, 59, and 40 species respectively. Moringa oleifera had 46 mentions for ailments like stomach pain, malaria fever, typhoid fever, and diarrhea. Azadirachta indica had 42 mentions for malaria fever, typhoid fever, stomach pain, and skin problems. Other species most mentioned were Carica papaya with 34 mentions for typhoid fever, stomach pain, cancer, and diarrhea, while M. indica had 32 mentions for malaria fever, heart disease, and diarrhea. Also, Persea americana was mentioned 29 times predominantly for heart disease and cholesterol reduction. M. oleifera, M. indica, A. indica, P. americana, C. papaya and E. camaldulensis have the highest use value of 0.700, 0.633, 0.61, 0.489, 0.456 and 0.367 respectively. In was concluded that M. oleifera, M. indica and A. indica were most mentioned for treating common diseases in southern Kaduna. It is therefore recommended that these and other species be conserved in the area for sustainability.